Onboard functional and molecular imaging: A design investigation for robotic multipinhole SPECT

A novel approach to multipinhole SPECT for myocardial perfusion imaging.

UNLABELLED Myocardial perfusion imaging with SPECT remains critically important for diagnosing, assessing, and evaluating treatment of coronary artery disease. However, conventional rotational SPECT suffers from prolonged study times because of relatively low detection efficiency. We therefore have investigated a multipinhole collimator that could improve the detection efficiency in cardiac SPE...

Collimator design for a multipinhole brain SPECT insert for MRI.

PURPOSE Brain single photon emission computed tomography (SPECT) imaging is an important clinical tool, with unique tracers for studying neurological diseases. Nowadays, most commercial SPECT systems are combined with x-ray computed tomography (CT) in so-called SPECT/CT systems to obtain an anatomical background for the functional information. However, while CT images have a high spatial resolu...

Design, Evaluation and Prototyping of a New Robotic Mechanism for Ultrasound Imaging

This paper presents a new robotic mechanism for ultrasound imaging. The device is placed on a patient's body by an operator, and an ultrasound expert controls the motions of the device to obtain ultrasound images. The paper focuses on the robotic mechanism that performs ultrasound imaging. The design of the mechanism is based on two approaches to produce center of motion for an ultrasound probe...

TITLE: Onboard SPECT for Localizing Functional and Molecular Targets in Metastatic Breast Cancer PRINCIPAL INVESTIGATOR:

Imaging capabilities of the Inveon SPECT system using single-and multipinhole collimators.

UNLABELLED The Inveon small-animal SPECT system comes with several types of multipinhole collimator plates. We evaluate here the performance measurements of the Inveon SPECT system using 6 different collimators: 3 dedicated for mouse imaging and 3 for rat imaging. METHODS The measured performance parameters include the sensitivity, the spatial resolution using line sources, the ultra-micro De...